At a glance
ClinicalIndex Comparison Record- ✓Age 40–80 years
- ✓IOP ≥24 and ≤32 mm Hg in at least one eye
- ✓IOP ≥21 and ≤32 mm Hg in the fellow eye
- ✓Normal visual fields and optic discs
- ✕Best-corrected visual acuity worse than 20/40 in either eye
- ✕Previous intraocular surgery
- ✕Secondary causes of elevated IOP
- ✕Angle-closure glaucoma or anatomically narrow angles
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Ocular Hypertension Treatment Study (OHTS)
In Brief
A Phase 3 clinical trial evaluating Topical ocular hypotensive eye drops. for Ocular Hypertension and Glaucoma. Completed, enrolled 1,636 participants.
Detailed Summary
To determine whether medical reduction of intraocular pressure prevents or delays the onset of glaucomatous visual field loss and/or optic disc damage in ocular hypertensive participants judged to be at moderate risk for developing open-angle glaucoma. To produce natural history data to assist in identifying patients at most risk for developing open-angle glaucoma and those most likely to benefit from early medical treatment. To quantify risk factors for developing open-angle glaucoma among ocular hypertensive individuals.
Study Details
Timeline
Interventions
Topical ocular hypotensive eye drops.