At a glance
ClinicalIndex Comparison RecordPhase 3Completed
Drug / intervention
propranolol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Multicenter Investigation of Limitation of Infarct Size (MILIS)
National Heart, Lung, and Blood Institute (NHLBI)·interventional·Posted Oct 28, 1999·Updated Jul 12, 2016
In Brief
A Phase 3 clinical trial evaluating propranolol and hyaluronidase for Cardiovascular Diseases and 4 related conditions. Completed.
Detailed Summary
To assess the ability of two separate therapeutic interventions, propranolol and hyaluronidase, to limit the ultimate size of an acute myocardial infarction. A secondary objective was to assess the influence of these therapies upon ventricular function and morbidity following myocardial infarction.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction, Myocardial Ischemia
Countries--
Collaborators--
Timeline
Phase 3CompletedFinished
197719781979198019811982198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartSep 1977
Study CompletionDec 1985
First PostedOct 1999
TodayJul 2026
First PostedOct 28, 1999
Enrollment StartSep 1, 1977
Study CompletionDec 1, 1985
TodayJul 2, 2026
Posted 26.7 years ago
Interventions
propranololdrug
hyaluronidasedrug