At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
In Brief
A Phase 2 clinical trial evaluating chlorthalidone, reserpine, and 2 other interventions for Cardiovascular Diseases and 3 related conditions. Completed.
Detailed Summary
The SHEP Pilot Study had six objectives, each designed to develop and test critical components of a full scale trial directed at the health consequences of treating isolated systolic hypertension (ISH) in the elderly. l. To estimate and compare the yield of participants for randomization into a clinical trial from various community groups using various recruitment techniques. 2\. To estimate compliance with the visit schedule and to the prescribed double-blind regimens. 3\. To estimate and compare the effectiveness of specified antihypertensive medications in reducing the blood pressure. 4\. To estimate and compare the unwanted effects of specified antihypertensive medication in an elderly population. 5\. To evaluate the feasibility and effectiveness of periodic behavioral assessment in this population. 6\. To develop and test methods of ascertaining stroke and other disease endpoints.