CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed
Drug / intervention
vitamin C +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00000541
NCT00000541Phase 2Completed
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Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

Brigham and Women's Hospital·interventional·Posted Oct 28, 1999·Updated Jul 15, 2020

In Brief

A Phase 2 clinical trial evaluating dietary supplements, vitamin C, and 3 other interventions for Cardiovascular Diseases and 5 related conditions. Completed.

Detailed Summary

To determine if supplements of vitamin C, vitamin E, beta-carotene, and B-vitamins (a combination of folic acid, vitamins B6 and B12) reduce risk of major cardiovascular events in high risk women with a prior history of atherosclerotic cardiovascular disease. The trial is a companion to the Women's Health Study (WHS), a primary prevention trial of vitamin E and aspirin in a low risk population of women.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases, Myocardial Infarction, Myocardial Ischemia
Countries--
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)

Timeline

Phase 2CompletedFinished
19931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 28, 1999
Enrollment StartMay 1, 1993
Primary CompletionJul 1, 2005
TodayJul 2, 2026
Enrollment to primary: 12.2 yearsPosted 26.7 years ago

Interventions

dietary supplementsbehavioral

vitamin Cdrug

vitamin Edrug

beta-carotenedrug

folic acid/Vitamin B6/Vitamin B12drug