CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed
Drug / intervention
amiodarone +13 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00000556
NCT00000556Phase 3Completed
CompareCT.gov

Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)

National Heart, Lung, and Blood Institute (NHLBI)·interventional·Posted Oct 28, 1999·Updated Mar 25, 2016

In Brief

A Phase 3 clinical trial evaluating amiodarone, sotalol, and 12 other interventions for Arrhythmia and 3 related conditions. Completed.

Detailed Summary

To compare two standard treatment strategies for atrial fibrillation: ventricular rate control and anticoagulation vs. rhythm control and anticoagulation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArrhythmia, Atrial Fibrillation, Cardiovascular Diseases, Heart Diseases
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 28, 1999
Enrollment StartMar 1, 1995
Study CompletionSep 1, 2002
TodayJul 2, 2026
Posted 26.7 years ago

Interventions

amiodaronedrug

sotaloldrug

propafenonedrug

flecainidedrug

quinidinedrug

moricizinedrug

disopyramidedrug

procainamidedrug

adrenergic beta antagonistsdrug

verapamildrug

diltiazemdrug

digoxindrug

catheter ablationprocedure

pacemaker, artificialdevice