At a glance
ClinicalIndex Comparison RecordPhase 3Completed
Drug / intervention
pacemaker, artificialdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Mode Selection Trial in Sinus Node Dysfunction (MOST)
In Brief
A Phase 3 clinical trial evaluating pacemaker, artificial for Arrhythmia and 5 related conditions. Completed.
Detailed Summary
To determine if dual chamber rate-modulated pacing (DDDR) in patients with sick sinus syndrome is superior to single chamber pacing (VVIR) with respect to subsequent frequency of adverse clinical events such as stroke, quality of life and function, and cost effectiveness.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArrhythmia, Cardiovascular Diseases, Heart Diseases, Sick Sinus Syndrome, Vascular Diseases, Cerebrovascular Accident
Countries--
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)
Timeline
Phase 3CompletedFinished
199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJun 1995
First PostedOct 1999
Study CompletionMay 2002
TodayJul 2026
First PostedOct 28, 1999
Enrollment StartJun 1, 1995
Study CompletionMay 1, 2002
TodayJul 2, 2026
Posted 26.7 years ago
Interventions
pacemaker, artificialdevice