CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed
Drug / intervention
Lysofylline +6 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00000579
NCT00000579Phase 3Completed

Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)

National Heart, Lung, and Blood Institute (NHLBI)·interventional·Posted Oct 28, 1999·Updated Mar 23, 2016

In Brief

A Phase 3 clinical trial evaluating Low Tidal Volume Ventilation, Positive End-Expiratory Pressure, and 5 other interventions for Respiratory Distress Syndrome, Adult and Lung Diseases. Completed, across 21 sites in 2 countries.

Detailed Summary

The purposes of this study are to assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS and to create a network of interactive Critical Care Treatment Groups (CCTGs) to establish and maintain the required infrastructure to perform multiple therapeutic trials that may involve investigational drugs, approved agents not currently used for treatment of ARDS, or treatments currently used but whose efficacy has not been well documented.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
1994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 28, 1999
Enrollment StartSep 1, 1994
Study CompletionJul 1, 2004
TodayJul 2, 2026
Posted 26.7 years ago

Interventions

Low Tidal Volume Ventilationprocedure

Positive End-Expiratory Pressureprocedure

Lysofyllinedrug

Methylprednisolonedrug

Ketoconazoledrug

Fluid Managementprocedure

Pulmonary Artery Catheterprocedure