At a glance
ClinicalIndex Comparison RecordPhase 3Completed
Drug / intervention
penicillindrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Penicillin Prophylaxis in Sickle Cell Disease (PROPS)
National Heart, Lung, and Blood Institute (NHLBI)·interventional·Posted Oct 28, 1999·Updated Mar 25, 2016
In Brief
A Phase 3 clinical trial evaluating penicillin for Anemia, Sickle Cell and 4 related conditions. Completed.
Detailed Summary
To determine whether the regular daily administration of oral penicillin would reduce the incidence of documented infection due to Streptococcus pneumoniae in children with sickle cell anemia.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnemia, Sickle Cell, Hematologic Diseases, Hemoglobinopathies, Infection (S. Pneumoniae), Pneumonia
Countries--
Collaborators--
Timeline
Phase 3CompletedFinished
198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartAug 1983
Study CompletionOct 1994
First PostedOct 1999
TodayJul 2026
First PostedOct 28, 1999
Enrollment StartAug 1, 1983
Study CompletionOct 1, 1994
TodayJul 2, 2026
Posted 26.7 years ago
Interventions
penicillindrug