At a glance

ClinicalIndex Comparison Record

Phase 3Completed· 129 enrolled

Drug / intervention

Left ventricular assist device +1 moredevice

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00000607

NCT00000607Phase 3Completed

Compare CT.gov

The REMATCH Trial: Rationale, Design, and End Points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure

Columbia University·interventional·Posted Oct 28, 1999·Updated Dec 23, 2015

In Brief

A Phase 3 clinical trial evaluating Left ventricular assist device and Optimal medical therapy for Cardiovascular Diseases and 3 related conditions. Completed, enrolled 129 participants across 1 site.

Detailed Summary

To conduct a randomized, unblinded clinical trial comparing the left ventricular assist device (LVAD) with maximum medical management in patients with end-stage heart failure who were not candidates for heart transplantation.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsCardiovascular Diseases, Heart Diseases, Heart Failure, Heart Failure, Congestive

CountriesUnited States

CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)

Timeline

Phase 3CompletedFinished

1997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartOct 1997

Primary CompletionMar 1999

First PostedOct 1999

TodayJul 2026

First PostedOct 28, 1999

Enrollment StartOct 1, 1997

Primary CompletionMar 1, 1999

TodayJul 2, 2026

Enrollment to primary: 1.4 yearsPosted 26.7 years ago

Interventions

Left ventricular assist devicedevice

A type of implantable heart pump

Optimal medical therapydevice

(non-experimental) One possibility in handling Heart failure effectively is optimal medicine therapy. The most popular treatment medications at present are ACE Inhibitors and Beta Blockers. The result is the heart being able to pump more effectively and allowing blood to circulate freely.