CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed
Drug / intervention
Vincristinedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00001689
NCT00001689Phase 1Completed
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A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia

National Cancer Institute (NCI)·interventional·Posted Nov 4, 1999·Updated Mar 4, 2008

In Brief

A Phase 1 clinical trial evaluating Vincristine for Acute Lymphocytic Leukemia and Leukemia. Completed, across 1 site.

Detailed Summary

The pharmacokinetic behavior of vincristine in pediatric patients has not been well characterized. The present study will obtain detailed information on vincristine pharmacokinetics in patients being treated for standard risk ALL on CCG protocols 1952/1962. A limited sampling strategy will be developed, and the interpatient and intrapatient variability of vincristine pharmacokinetics in children will be studied. A correlation between vincristine neurotoxicity and vincristine pharmacokinetics will be sought.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Lymphocytic Leukemia, Leukemia
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 4, 1999
Enrollment StartJan 1, 1998
Study CompletionNov 1, 2003
TodayJul 2, 2026
Posted 26.7 years ago

Interventions

Vincristinedrug