CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 35 enrolled
Drug / intervention
filgrastim +9 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00002461
NCT00002461Phase 2Completed

Phase II Study of Intensive Carmustine and Etoposide With Cisplatin or Cyclophosphamide, Followed By Rescue With Autologous Bone Marrow Treated In Vitro With Etoposide and/or Peripheral Blood Stem Cells Mobilized With Filgrastim (G-CSF) or Sargramostim (GM-CSF) With or Without Radiotherapy in Patients With Resistant Hodgkin's Disease or Non-Hodgkin's Lymphoma

Montefiore Medical Center·interventional·Posted Mar 26, 2004·Updated Aug 17, 2018

In Brief

A Phase 2 clinical trial evaluating filgrastim, sargramostim, and 8 other interventions for Lymphoma. Completed, enrolled 35 participants across 1 site.

Detailed Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Bone marrow or peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy to kill more cancer cells. PURPOSE: This phase II trial is studying giving high-dose chemotherapy followed by bone marrow or peripheral stem cell transplantation to see how well it works in treating patients with refractory Hodgkin's disease or non-Hodgkin's lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLymphoma
CountriesUnited States

Timeline

Phase 2CompletedFinished
1988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 26, 2004
Enrollment StartApr 1, 1988
Primary CompletionJul 1, 1991
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 22.3 years ago

Interventions

filgrastimbiological

sargramostimbiological

carmustinedrug

cisplatindrug

cyclophosphamidedrug

etoposidedrug

autologous bone marrow transplantationprocedure

in vitro-treated bone marrow transplantationprocedure

peripheral blood stem cell transplantationprocedure

radiation therapyradiation