CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed
Drug / intervention
cytarabine +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00002517
NCT00002517Phase 3Completed

IDA VS MTZ IN INDUCTION AND INTENSIFICATION TREATMENT OF AML OR MDS IN CHILDREN, A PHASE III RANDOMIZED STUDY

European Organisation for Research and Treatment of Cancer - EORTC·interventional·Posted Jan 27, 2003·Updated Jun 22, 2010

In Brief

A Phase 3 clinical trial evaluating cytarabine, daunorubicin hydrochloride, and 7 other interventions for Leukemia and Myelodysplastic Syndromes. Completed, across 23 sites in 3 countries.

Detailed Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which regimen of combination chemotherapy is more effective for acute myeloid leukemia or myelodysplastic syndrome. PURPOSE: Randomized phase III trial to compare the effectiveness of different combination chemotherapy regimens in treating children who have newly diagnosed acute myeloid leukemia or myelodysplastic syndrome.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, France, Portugal
Collaborators--

Timeline

Phase 3CompletedFinished
19931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 27, 2003
Enrollment StartMar 1, 1993
Primary CompletionMay 1, 2010
TodayJul 2, 2026
Enrollment to primary: 17.2 yearsPosted 23.4 years ago

Interventions

cytarabinedrug

daunorubicin hydrochloridedrug

dexamethasonedrug

etoposidedrug

idarubicindrug

mitoxantrone hydrochloridedrug

thioguaninedrug

allogeneic bone marrow transplantationprocedure

radiation therapyradiation