CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 500 target
Drug / intervention
carboplatin +16 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00002802
NCT00002802Phase 3Completed

PHASE III MULTICENTRE TRIAL OF TREATMENT OF NEUROBLASTOMA IN CHILDREN AND ADOLESCENTS

Children's Hospital Medical Center, Cincinnati·interventional·Posted May 12, 2004·Updated Dec 19, 2013

In Brief

A Phase 3 clinical trial evaluating carboplatin, cisplatin, and 15 other interventions for Neuroblastoma. Completed, enrolled 500 participants across 1 site.

Detailed Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which treatment regimen is most effective in treating patients with different stages of and risk factors for neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of therapy based on stage of disease and risk assessment in treating children with neuroblastoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNeuroblastoma
CountriesGermany
Collaborators--

Timeline

Phase 3CompletedFinished
19901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 12, 2004
Enrollment StartJul 1, 1990
Study CompletionSep 1, 2003
TodayJul 2, 2026
Posted 22.1 years ago

Interventions

carboplatindrug

cisplatindrug

cyclophosphamidedrug

dacarbazinedrug

doxorubicin hydrochloridedrug

etoposidedrug

ifosfamidedrug

melphalandrug

mesnadrug

vincristine sulfatedrug

vindesinedrug

autologous bone marrow transplantationprocedure

conventional surgeryprocedure

low-LET cobalt-60 gamma ray therapyradiation

low-LET electron therapyradiation

low-LET photon therapyradiation

radioisotope therapyradiation