CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
Antineoplaston therapy (Atengenal + Astugenal)drug
Likely dose
Antineoplaston therapy (Atengenal + Astugenal); specific dose not statedAI-extracted
Key inclusion· 6
  • Histologically confirmed brain tumor (except brainstem locations) that is unlikely to respond to existing therapy and for which no curative therapy exists
  • Evidence of persistent or recurrent brain tumor on MRI scan performed within two weeks prior to study entry
  • Tumor must be at least 5 mm in size
  • Age 18 years and over
Key exclusion· 9
  • Brain tumors located in the brainstem
  • No prior antineoplaston therapy
  • Hepatic failure
  • History of renal conditions that contraindicate high dosages of sodium

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00003457
NCT00003457Phase 2Completed

Phase II Study Of Antineoplastons A10 And AS2-1 In Patients With Brain Tumors.

Burzynski Research Institute·interventional·Posted Jan 27, 2003·Updated Aug 22, 2017

In Brief

A Phase 2 clinical trial evaluating Antineoplaston therapy (Atengenal + Astugenal) for Refractory Brain Tumors. Completed, enrolled 40 participants across 1 site.

Detailed Summary

RATIONALE: Current therapies for adults with persistent or recurrent brain tumors provide very limited benefit to the patient. The anti-cancer properties of Antineoplaston therapy suggest that it may prove beneficial in the treatment of adults with persistent or recurrent brain tumors. PURPOSE: This study is being performed to determine the effects (good and bad) that Antineoplaston therapy has on adults with persistent or recurrent brain tumors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
19961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 27, 2003
Enrollment StartJul 1, 1996
Primary CompletionFeb 1, 2012
TodayJul 2, 2026
Enrollment to primary: 15.6 yearsPosted 23.4 years ago

Interventions

Antineoplaston therapy (Atengenal + Astugenal)drug

Adults with a persistent or recurrent brain tumor will receive Antineoplaston therapy (Atengenal + Astugenal).