CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 31 enrolled
Drug / intervention
Antineoplaston therapy (Atengenal + Astugenal)drug
Likely dose
Antineoplaston A10 and AS2-1 in divided daily doses given as six infusions at 4-hourly intervalsAI-extracted
Key inclusion· 9
  • Histologically proven stage II, III, or IV low-grade non-Hodgkin's lymphoma
  • Unlikely to respond to existing therapy or no established therapy exists
  • Age 18 and over
  • Karnofsky performance status 60-100%
Key exclusion· 7
  • History of renal conditions that contraindicate high dosages of sodium
  • Hypertension
  • History of congestive heart failure
  • History of cardiovascular conditions that contraindicate high dosages of sodium

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00003499
NCT00003499Phase 2Completed

Phase II Study of Antineoplaston A10 and AS2-1 in Patients With Non-Hodgkin's Lymphoma Low Grade

Burzynski Research Institute·interventional·Posted Jan 27, 2003·Updated Nov 24, 2020

In Brief

A Phase 2 clinical trial evaluating Antineoplaston therapy (Atengenal + Astugenal) for Low-Grade Lymphoma. Completed, enrolled 31 participants across 1 site.

Detailed Summary

Current therapies for Low-grade Non-Hodgkin's Lymphoma provide limited benefit to the patient. The anti-cancer properties of Antineoplaston therapy suggest that it may prove beneficial in the treatment of Low-grade Non-Hodgkin's Lymphoma. PURPOSE: This study is being performed to determine the effects (good and bad) that Antineoplaston therapy has on patients with Low-grade Non-Hodgkin's Lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
19961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 27, 2003
Enrollment StartMar 6, 1996
Primary CompletionSep 13, 2003
TodayJul 2, 2026
Enrollment to primary: 7.5 yearsPosted 23.4 years ago

Interventions

Antineoplaston therapy (Atengenal + Astugenal)drug

Patients with Low-grade non-Hodgkin's lymphoma will receive Antineoplaston therapy (Atengenal + Astugenal). The daily doses of A10 and AS2-1 are divided into six infusions, which are given at 4-hourly intervals. Each infusion starts with infusion of A10 and is immediately followed by infusion of AS2-1.