At a glance
ClinicalIndex Comparison RecordN/ACompleted
Drug / intervention
pergolidedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Study of Pergolide in Children With Tourette Syndrome
Children's Hospital Medical Center, Cincinnati·interventional·Posted Oct 19, 1999·Updated Mar 25, 2015
In Brief
A clinical study evaluating pergolide for Tourette Syndrome. Completed.
Detailed Summary
OBJECTIVES: I. Evaluate the presumed mechanism of action of low dose pergolide to act acutely through the dopaminergic autoreceptor or postsynaptically at D2 sites in children 7 to 17 with tourette syndrome (GTS). II. Compare tolerability and safety of pergolide in these patients to standard neuroleptic therapy via naturalist assessment after 3-6 months of treatment using matched historical controls on neuroleptics. III. Determine efficacy of pergolide for tic control in these patients.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTourette Syndrome
Countries--
Collaborators--
Timeline
N/ACompletedFinished
199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartDec 1994
First PostedOct 1999
Study CompletionSep 2002
TodayJul 2026
First PostedOct 19, 1999
Enrollment StartDec 1, 1994
Study CompletionSep 1, 2002
TodayJul 2, 2026
Posted 26.7 years ago
Interventions
pergolidedrug