At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
CSP #430 - Reducing The Efficacy-Effectiveness Gap In Bipolar Disorder
In Brief
A Phase 3 clinical trial evaluating Bipolar Disorder Program and Usual (psychiatric) Care for Bipolar Disorder. Completed, enrolled 382 participants across 13 sites.
Detailed Summary
Based on highly promising preliminary data, it is proposed to conduct a multi-site randomized controlled trial of a high-intensity ambulatory treatment program for bipolar disorder against standard office-based, physician-centered care. The major characteristics of this program are that it emphasizes (1) aggressive guideline-driven pharmacotherapy, (2) continuity of care with identified primary mental health nurse clinicians supported by psychiatrist back-up, and (3) patient education to improve treatment alliance and illness management skills.