At a glance
ClinicalIndex Comparison RecordN/ACompleted· 400 target
Drug / intervention
Not specified
Likely dose
Not stated in record
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Human Sperm Zona Acceptor: Environmental Effects
National Institute of Environmental Health Sciences (NIEHS)·observational·Posted Mar 12, 2001·Updated Apr 15, 2015
In Brief
An observational study for Male Infertility and 3 related conditions. Completed, enrolled 400 participants across 3 sites.
Detailed Summary
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 2001
Enrollment StartAug 2002
Primary CompletionJul 2007
TodayJul 2026
First PostedMar 12, 2001
Enrollment StartAug 1, 2002
Primary CompletionJul 1, 2007
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 25.3 years ago