CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 42 enrolled
Drug / intervention
filgrastim +15 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00017368
NCT00017368Phase 2Completed

A Pilot Study Of Tandem High Dose Chemotherapy With Stem Cell Rescue Following Induction Therapy In Children With High Risk Neuroblastoma

Children's Oncology Group·interventional·Posted Oct 9, 2003·Updated Feb 13, 2014

In Brief

A Phase 2 clinical trial evaluating filgrastim, sargramostim, and 14 other interventions for Neuroblastoma. Completed, enrolled 42 participants across 9 sites in 2 countries.

Detailed Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating children who have newly diagnosed neuroblastoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNeuroblastoma
CountriesAustralia, United States

Timeline

Phase 2CompletedFinished
200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 9, 2003
Enrollment StartApr 1, 2001
Primary CompletionSep 1, 2005
Study CompletionJan 1, 2012
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 22.7 years ago

Interventions

filgrastimbiological

sargramostimbiological

carboplatindrug

cisplatindrug

cyclophosphamidedrug

doxorubicin hydrochloridedrug

etoposidedrug

etoposide phosphatedrug

ifosfamidedrug

isotretinoindrug

melphalandrug

thiotepadrug

vincristine sulfatedrug

conventional surgeryprocedure

peripheral blood stem cell transplantationprocedure

radiation therapyradiation