At a glance

ClinicalIndex Comparison Record

Phase 4Completed· 270 enrolled

Drug / intervention

Single-injection femoral nerve block +2 moreprocedure

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00022854

NCT00022854Phase 4Completed

Compare CT.gov

Outcomes After ACL Reconstruction: The Effect of Femoral Nerve Block Analgesia

University of Pittsburgh·interventional·Posted Aug 16, 2001·Updated May 3, 2013

In Brief

A Phase 4 clinical trial evaluating Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, and 1 other intervention for Anterior Cruciate Ligament Rupture. Completed, enrolled 270 participants across 1 site.

Detailed Summary

Anterior cruciate ligament (ACL) reconstruction is surgery that is done to repair a damaged ligament in the knee. In this study we will look at whether the femoral nerve block, a commonly used method for pain relief after ACL reconstruction, affects the way patients feel after surgery. We will study recovery during the first week after surgery and also 3-12 weeks after surgery. We will give all patients spinal anesthesia. Some patients will also receive a continuous femoral nerve block for 2 days, or by a single injection. We predict that patients who received the nerve block will have significantly improved pain results, compared to patients who did not receive the nerve block.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsAnterior Cruciate Ligament Rupture

CountriesUnited States

CollaboratorsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Timeline

Phase 4CompletedFinished

200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartMay 2001

First PostedAug 2001

Study CompletionJan 2005

TodayJul 2026

First PostedAug 16, 2001

Enrollment StartMay 1, 2001

Study CompletionJan 1, 2005

TodayJul 2, 2026

Posted 24.9 years ago

Interventions

Single-injection femoral nerve blockprocedure

Nerve block bolus with 30 mL levobupivacaine 0.25%, followed by continuous saline infusion

Femoral nerve block 60-hour continuous injectionprocedure

Nerve block bolus with 30 mL levobupivacaine 0.25%, followed by continuous infusion (5 mL/hr for 50 hours) of 0.25% levobupivacaine

Saline (control) injection into femoral nerve envelopeprocedure

Nerve block bolus with 30 mL saline, followed by continuous saline infusion