CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,277 enrolled
Drug / intervention
Ferritin reduction to 25 ng/ml by phlebotomyprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00032357
NCT00032357Phase 3Completed
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CSP #410 - The Iron (Fe) and Atherosclerosis Study (FeAST)

US Department of Veterans Affairs·interventional·Posted Mar 20, 2002·Updated Jan 21, 2013

In Brief

A Phase 3 clinical trial evaluating Ferritin reduction to 25 ng/ml by phlebotomy for Atherosclerosis and 2 related conditions. Completed, enrolled 1,277 participants across 24 sites in 2 countries.

Detailed Summary

Veterans Affairs Cooperative Study #410, The Iron and Atherosclerosis Trial, FeAST, a 24-hospital prospective randomized single-blinded clinical trial of graded iron reduction was conducted between May 1, 1999 and April 30, 2005, and has now been completed. A total of 1,277 primarily male participants with peripheral arterial disease were entered. The primary outcome was all cause mortality and the secondary outcome combined death plus non-fatal myocardial infarction (MI) and stroke.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtherosclerosis, Intermittent Claudication, Peripheral Vascular Diseases
CountriesPuerto Rico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
19992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 20, 2002
Enrollment StartMay 1, 1999
Primary CompletionApr 1, 2005
Study CompletionSep 1, 2005
TodayJul 2, 2026
Enrollment to primary: 5.9 yearsPosted 24.3 years ago

Interventions

Ferritin reduction to 25 ng/ml by phlebotomyprocedure