CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 40 enrolled
Drug / intervention
embryonic dopamine cell implant surgery +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00038116
NCT00038116Phase 3Completed
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Embryonic Dopamine Cell Implants for Parkinson's Disease: A Double-Blind Study

University of Colorado, Denver·interventional·Posted May 30, 2002·Updated Feb 5, 2013

In Brief

A Phase 3 clinical trial evaluating embryonic dopamine cell implant surgery and placebo for Parkinson Disease. Completed, enrolled 40 participants across 3 sites.

Detailed Summary

The purpose of this trial is to determine if patients who received embryonic dopamine cell implant surgery showed significantly greater improvement in their Parkinson's disease than a control group undergoing the placebo treatment, and to determine if the cell implant surgery was more effective in younger or older patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsParkinson Disease
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 30, 2002
Enrollment StartMay 1, 1995
Primary CompletionAug 1, 2009
TodayJul 2, 2026
Enrollment to primary: 14.3 yearsPosted 24.1 years ago

Interventions

embryonic dopamine cell implant surgeryprocedure

Half of the participants received the cell implant surgery, while the other half received the placebo. After the double-blind phase of the study, patients in the placebo group had the option of receiving tissue implants. Fourteen of these patients eventually had transplants.

placeboprocedure

sham surgery