CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 745 enrolled
Drug / intervention
ginger +1 moredietary
Likely dose
Ginger dose not specified in trial recordAI-extracted
Key inclusion· 6
  • ✓Diagnosis of cancer and scheduled to receive at least 3 courses of chemotherapy
  • ✓Must have experienced nausea of any degree of severity after completion of the first study-related course of chemotherapy
  • ✓Received a 5-HT3 receptor antagonist antiemetic with dexamethasone on day 1 of course 1 of chemotherapy
  • ✓Scheduled to receive a 5-HT3 receptor antagonist antiemetic with dexamethasone on day 1 of courses 2 and 3 of chemotherapy
Key exclusion· 9
  • ✕Symptomatic brain metastases
  • ✕Prior bleeding or blood coagulation disorder (e.g., thrombocytopenia or platelet dysfunction)
  • ✕Prior coagulation factor deficiency
  • ✕Prior vascular defect

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00040742
NCT00040742Phase 3Completed
CompareCT.gov

A Phase II/III Randomized, Controlled Clinical Trial Of Ginger (Zingiber Officinale) For Nausea Caused By Chemotherapy For Cancer

Gary Morrow·interventional·Posted Jan 27, 2003·Updated Nov 9, 2015

In Brief

A Phase 3 clinical trial evaluating ginger and placebo for Nausea and Vomiting. Completed, enrolled 745 participants across 19 sites.

Detailed Summary

RATIONALE: Ginger may help reduce or prevent nausea. It is not yet known if antiemetic drugs are more effective with or without ginger in treating nausea caused by chemotherapy. PURPOSE: This randomized phase II/III trial is studying giving antiemetic drugs together with ginger to see how well they work compared to antiemetic drugs alone in treating nausea in patients who are receiving chemotherapy for cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNausea, Vomiting
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 3CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 27, 2003
Enrollment StartMar 1, 2003
Primary CompletionAug 1, 2011
Study CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 8.4 yearsPosted 23.4 years ago

Interventions

gingerdietary

Given orally

placeboother

Given orally