CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 488 enrolled
Drug / intervention
Sertraline (SRT) +2 moredrug
Likely dose
Not stated in record
Key inclusion· 1
  • ✓DSM-IV criteria for separation anxiety disorder, social phobia, or generalized anxiety disorder
Key exclusion· 1
  • ✕Major neurological disorder or medical illness that would interfere with participation in the study

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00052078
NCT00052078Phase 3Completed
CompareCT.gov

Child/Adolescent Anxiety Multimodal Treatment Study

Johns Hopkins University·interventional·Posted Jan 23, 2003·Updated Sep 19, 2017

In Brief

A Phase 3 clinical trial evaluating Sertraline (SRT), Cognitive Behavioral Therapy (CBT), and 1 other intervention for Anxiety Disorders and 2 related conditions. Completed, enrolled 488 participants across 6 sites.

Detailed Summary

This randomized, controlled trial compared the efficacy of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety Disorders, Social Phobia, Generalized Anxiety Disorder
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

Phase 3CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 23, 2003
Enrollment StartJan 1, 2003
Primary CompletionOct 1, 2007
Study CompletionMar 1, 2008
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 23.4 years ago

Interventions

Sertraline (SRT)drug

Participants were treated with sertraline.

Cognitive Behavioral Therapy (CBT)behavioral

Participants received CBT.

Placebodrug

Participants were treated with a placebo pill.