CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 905 enrolled
Drug / intervention
Prasugrel (CS-747) +1 moredrug
Likely dose
Not stated in record
Key inclusion· 2
  • Candidate for elective or urgent PCI with intended coronary stenting
  • Age 18–75 years
Key exclusion· 5
  • Acute ST-elevation myocardial infarction (STEMI) as indication for PCI
  • Oral anticoagulation therapy that cannot be safely discontinued
  • Cardiogenic shock or severe congestive heart failure
  • Active internal bleeding or history of bleeding diathesis

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00059215
NCT00059215Phase 2Completed

A Double-Blind, Randomized, Multicenter, Dose-Ranging Trial of CS-747 Compared With Clopidogrel in Subjects Undergoing Percutaneous Coronary Intervention

Eli Lilly and Company·interventional·Posted Apr 23, 2003·Updated May 25, 2010

In Brief

A Phase 2 clinical trial evaluating Prasugrel (CS-747) and Clopidogrel for Cardiovascular Diseases and Heart Diseases. Completed, enrolled 905 participants across 2 sites in 2 countries.

Detailed Summary

The purpose of this study is to evaluate the effects of a drug known as CS-747 (also known as prasugrel) on subjects having a procedure called a percutaneous coronary intervention (also referred to as PCI) in which a doctor will attempt to open a blocked vessel (or vessels) in the heart using a catheter (a long thin tube) that has a small balloon on the end. In many cases, patients who have this procedure receive a stent, a small wire spring that helps keep the vessel open.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 23, 2003
Enrollment StartApr 1, 2003
Primary CompletionJan 1, 2004
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 23.2 years ago

Interventions

Prasugrel (CS-747)drug

Administered orally

Clopidogreldrug

Administered orally