CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 319 enrolled
Drug / intervention
Modern medical management +3 moredrug
Likely dose
Not stated in record
Key inclusion· 3
  • Symptomatic heart failure NYHA Class II-IV within 3 months of entry
  • Left ventricular ejection fraction <35% by CMR or gated SPECT
  • Coronary anatomy suitable for revascularization
Key exclusion· 7
  • Primary valvular heart disease requiring valve repair or replacement
  • Cardiogenic shock or requiring inotropic/intra-aortic balloon support
  • PCI planned for CAD treatment
  • Acute myocardial infarction within 30 days

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00074724
NCT00074724N/ACompleted

Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization

Medstar Health Research Institute·interventional·Posted Dec 23, 2003·Updated Apr 8, 2021

In Brief

A clinical study evaluating Coronary Artery Bypass, Modern medical management, and 2 other interventions for Cardiovascular Diseases and 4 related conditions. Completed, enrolled 319 participants.

Detailed Summary

To define the role of the assessment of myocardial viability with dobutamine echocardiography (DE) in the clinical evaluation and selection of the best treatment for a high-risk subset of patients with coronary artery disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--

Timeline

N/ACompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 23, 2003
Enrollment StartMay 1, 2003
Primary CompletionDec 1, 2008
Study CompletionApr 1, 2017
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 22.5 years ago

Interventions

Coronary Artery Bypassprocedure

coronary revascularization using arterial or vein conduits

Modern medical managementdrug

Therapies with evidence-based recommendations.

Dobutamine echocardiographydevice

Incremental dose administration of dobutamine to elicit a contractile response of the myocardium.

Optimal medical therapydrug

All medical interventions known to improve outcomes in patients with ischemic left ventricular dysfunction.