At a glance
ClinicalIndex Comparison Record- ✓Postmenopausal: no menstrual period for 12 months or no period for 6-12 months with FSH >40 IU/L
- ✕Prior estrogen, progesterone, raloxifene, or tamoxifen therapy
- ✕Prior bisphosphonates, calcitonin, fluoride, or systemic corticosteroids
- ✕Soy or herbal supplements (including DHEA) within 3 months
- ✕Antibiotics in the month prior to study entry
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Bone Sparing Effects of Soy Phytoestrogens in Menopause
In Brief
A Phase 3 clinical trial evaluating Soy isoflavones and Placebo for Menopause and 2 related conditions. Completed, enrolled 248 participants across 1 site.
Detailed Summary
The purpose of this study is to determine if soy-derived phytoestrogens (naturally occurring compounds similar to estrogen) can prevent bone loss and other menopausal symptoms in women who have recently gone through menopause. Study hypothesis: Tablets of high-dose, purified soy phytoestrogens spare the normally occurring spinal bone loss and improve biological and other emotional changes of menopause.
Study Details
Timeline
Interventions
Purified soy isoflavones (phytoestrogens) in tablet form tablets; 200 mg.
Placebo soy isoflavones