At a glance
ClinicalIndex Comparison Record- ✓Age 10–17 years inclusive
- ✓Confirmed history of sexual abuse
- ✓At least 5 PTSD symptoms documented on KSADS-PL with symptoms present in each of the three clusters (reexperiencing, avoidance, arousal)
- ✓Parent or primary caregiver must be available and willing to participate in treatment
- ✕Non-English speaking
- ✕Schizophrenia or other severe psychotic disorder
- ✕Intellectual disability (IQ <60) or pervasive developmental disorder preventing CBT treatment
- ✕Currently taking psychotropic medication
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pharmacologic Treatment of PTSD in Sexually Abused Children
In Brief
A Phase 3 clinical trial evaluating Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill, and 1 other intervention for Stress Disorders, Post-Traumatic. Completed, enrolled 24 participants across 1 site.
Detailed Summary
This study will evaluate the benefit of adding sertraline (Zoloft®) to Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for sexually abused children who have Posttraumatic Stress Disorder (PTSD).
Study Details
Timeline
Interventions
12 weeks of Trauma-Focused CBT (TF-CBT)for youth and parent
12 weeks of Sertraline pill, flexible dosage of 50-150 mg/day, to be administered while receiving TF-CBT
12 weeks of Placebo pill, flexible dosage, of 50-150 mg/day, to be administered while receiving TF-CBT