CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 114 enrolled
Drug / intervention
Coping Skills Training +1 morebehavioral
Likely dose
Not stated in record
Key inclusion· 4
  • Diagnosis of juvenile primary fibromyalgia syndrome (JPFS) based on widespread pain for over 3 months, at least 5 tender points, and associated features (sleep difficulty, fatigue, abdominal discomfort)
  • Average pain intensity greater than 4 on the Visual Analog Scale
  • Functional disability score greater than 7
  • Stable medications for 8 weeks prior to study entry
Key exclusion· 4
  • Other chronic rheumatic diseases such as juvenile rheumatoid arthritis or lupus
  • Significant developmental delay or impairments including autism, cerebral palsy, or intellectual disability
  • Current or lifetime psychiatric diagnosis meeting DSM-IV criteria for panic disorder, bipolar disorder, major depressive disorder, or psychosis
  • Chronic opioid medications for fibromyalgia pain treatment

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00086047
NCT00086047Phase 3Completed

Randomized Clinical Trial in Juvenile Fibromyalgia

Children's Hospital Medical Center, Cincinnati·interventional·Posted Jun 23, 2004·Updated Sep 20, 2017

In Brief

A Phase 3 clinical trial evaluating Coping Skills Training and Education for Fibromyalgia. Completed, enrolled 114 participants across 3 sites.

Detailed Summary

Juvenile fibromyalgia is a chronic pain condition that can cause considerable suffering and difficulty in an adolescent's day-to-day activities. The purpose of this study is to determine whether coping skills training, when combined with usual medical care, can reduce pain and disability in adolescents with fibromyalgia. Study hypotheses: 1) Adolescents who receive coping skills training combined with their usual medical care will show significantly greater reductions in functional disability, pain, and depressive symptoms at the end of the acute treatment phase than adolescents who receive fibromyalgia education with their usual medical care. 2) Adolescents who receive coping skills training with their usual medical care will show significantly lower levels of functional disability, pain, and depressive symptoms at the end of a six-month maintenance phase than adolescents who receive fibromyalgia education with their usual medical care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFibromyalgia
CountriesUnited States

Timeline

Phase 3CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 23, 2004
Enrollment StartJul 1, 2004
Primary CompletionJul 1, 2010
TodayJul 2, 2026
Enrollment to primary: 6 yearsPosted 22.0 years ago

Interventions

Coping Skills Trainingbehavioral

8 weekly sessions of behavioral treatment

Educationbehavioral

8 weekly sessions of fibromyalgia education