At a glance
ClinicalIndex Comparison Record- ✓Light smokers smoking 6-15 cigarettes per day
- ✓Mentally and physically stable
- ✓Non-pregnant
None specified.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparing Smoking Treatment Programs for Lighter Smokers
In Brief
A Phase 2 clinical trial evaluating nicotine transdermal system, bupropion, and 4 other interventions for Tobacco Use Disorder. Completed, enrolled 260 participants across 1 site.
Detailed Summary
The purpose of this study was to compare two different types of Food and Drug Administration (FDA) approved smoking cessation medications (nicotine patch or bupropion) used in conjunction with two levels of counseling. It was hypothesized that the higher level of counseling would have the highest rates of treatment completion and highest rates of abstinence.
Study Details
Timeline
Interventions
starting with 21 or 14mg dependent on number of cigarettes per day smoked upon entry in the study; titrated down over 8 weeks.
150 mg/day X 3 days 300mg/day for 60 days Total 9 weeks
Brief manual based therapy; four 15 minute session over 10 weeks.
Manual based therapy; Weekly 30 minute sessions for 10 weeks
placebo patch containing no nicotine
placebo pills