At a glance
ClinicalIndex Comparison RecordN/ACompleted· 453 enrolled
Drug / intervention
Pharmacotherapy +2 moredrug
Likely dose
Not stated in record
Key inclusion· 5
- ✓Recently underwent CABG (combined or redo procedure) at one of 8 Pittsburgh area study hospitals
- ✓PHQ score >10 (for depressed cohort) OR PHQ score <5 (for non-depressed control)
- ✓MMSE score ≥24 (cognitive intact)
- ✓Able to be evaluated and treated for depression as an outpatient post CABG
Key exclusion· 10
- ✕Presently in treatment with a mental health specialist
- ✕Actively suicidal
- ✕History of psychotic illness
- ✕History of bipolar illness
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Treatment of Depression Following Bypass Surgery
In Brief
A clinical study evaluating Psychoeducation; Treatment recommendations, Pharmacotherapy, and 1 other intervention for Cardiovascular Diseases and 3 related conditions. Completed, enrolled 453 participants across 1 site.
Detailed Summary
The purpose of this study is to treat depression in patients who have undergone coronary artery bypass graft (CABG).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiovascular Diseases, Coronary Disease, Heart Diseases, Depression
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)
Timeline
N/ACompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartAug 2003
First PostedSep 2004
Primary CompletionJun 2008
Study CompletionDec 2009
TodayJul 2026
First PostedSep 23, 2004
Enrollment StartAug 1, 2003
Primary CompletionJun 1, 2008
Study CompletionDec 1, 2009
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 21.8 years ago
Interventions
Psychoeducation; Treatment recommendationsbehavioral
Counseling program
Pharmacotherapydrug
Recommendations to patients' PCP for medication to treat depression
Usual Careother
Physicians' Usual care