CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 59 enrolled
Drug / intervention
radiation therapyradiation
Likely dose
Not stated in record
Key inclusion· 5
  • ✓Age 3 to 21 years
  • ✓Histologically confirmed medulloblastoma or pineoblastoma
  • ✓Standard-risk or high-risk disease
  • ✓Biopsy or attempted surgical resection of tumor within past 35 days
Key exclusion· 5
  • ✕Prior radiotherapy
  • ✕More than 1 prior chemotherapy regimen
  • ✕Prior IV or intrathecal methotrexate
  • ✕Prior intrathecal thiotepa

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00105560
NCT00105560N/ACompleted
CompareCT.gov

Phase II Study of Craniospinal and Posterior Fossa Irradiation Using Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma: Assessment of Acute and Long Term Sequelae

Massachusetts General Hospital·interventional·Posted Mar 16, 2005·Updated Dec 28, 2021

In Brief

A clinical study evaluating radiation therapy for Brain and Central Nervous System Tumors and Long-term Effects Secondary to Cancer Therapy in Children. Completed, enrolled 59 participants across 1 site.

Detailed Summary

RATIONALE: Specialized radiation therapy that delivers radiation directly to the area where a tumor was surgically removed may kill any remaining tumor cells and cause less damage to normal tissue. PURPOSE: This phase II trial is studying how well proton beam radiation therapy works in treating young patients who have undergone biopsy or surgery for medulloblastoma or pineoblastoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain and Central Nervous System Tumors, Long-term Effects Secondary to Cancer Therapy in Children
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 16, 2005
Enrollment StartMay 1, 2002
Primary CompletionDec 1, 2012
Study CompletionDec 1, 2020
TodayJul 2, 2026
Enrollment to primary: 10.6 yearsPosted 21.3 years ago

Interventions

radiation therapyradiation

Radiation therapy with proton beam to standard doses