CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 441 enrolled
Drug / intervention
Comparator: Sitagliptin +2 moredrug
Likely dose
Sitagliptin 10 mg orally once dailyAI-extracted
Key inclusion· 1
  • Type 2 Diabetes Mellitus with inadequate glycemic control
Key exclusion· 1
  • Type 1 Diabetes Mellitus

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00106704
NCT00106704Phase 3Completed

A Multicenter, Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of the Addition of MK0431 to Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Glimepiride Alone or in Combination With Metformin

Merck Sharp & Dohme LLC·interventional·Posted Mar 30, 2005·Updated Jul 1, 2015

In Brief

A Phase 3 clinical trial evaluating Comparator: Sitagliptin, Comparator: Placebo, and 1 other intervention for Diabetes Mellitus, Type 2. Completed, enrolled 441 participants.

Detailed Summary

The purpose of this clinical study is to determine the safety and efficacy of an investigational drug in patients with Type 2 diabetes mellitus.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 30, 2005
Enrollment StartMar 1, 2005
Primary CompletionJun 1, 2006
Study CompletionJan 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 21.3 years ago

Interventions

Comparator: Sitagliptindrug

sitagliptin 10 mg tablet, once daily for 54 weeks

Comparator: Placebodrug

Placebo oral tablet once daily for 24 weeks

Comparator: Pioglitazonedrug

Pioglitazone 30 mg tablet once daily for 30 weeks