At a glance
ClinicalIndex Comparison Record- ✓Suspicious lung nodule for clinical stage I NSCLC, ≤3 cm maximum diameter (clinical stage Ia or selected Ib with visceral pleural involvement)
- ✓ECOG performance status 0, 1, or 2
- ✓Meet at least one major criterion (FEV1 ≤50% predicted OR DLCO ≤50% predicted) OR minimum two minor criteria
- ✓CT chest with upper abdomen within 60 days prior to pre-registration
- ✕Prior intra-thoracic radiation therapy
- ✕Prior invasive malignancy, unless disease-free ≥5 years (exceptions: non-melanoma skin cancer, in-situ cancers)
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Phase III Study of Sublobar Resection Versus Sublobar Resection Plus Brachytherapy in High Risk Patients With Non-Small Cell Lung Cancer (NSCLC), 3cm or Smaller
In Brief
A Phase 3 clinical trial evaluating surgery and brachytherapy for Lung Cancer. Completed, enrolled 224 participants across 38 sites in 2 countries.
Detailed Summary
This randomized phase III trial studies surgery and internal radiation therapy to see how well they work compared to surgery alone in treating patients with stage I non-small cell lung cancer. Surgery may be an effective treatment for non-small cell lung cancer. Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells. It is not yet known whether surgery and internal radiation therapy are more effective than surgery alone in treating non-small cell lung cancer.