At a glance
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Greenwich Lumbar Stenosis SLIP Study: A Multi-center, Randomized, Prospective Clinical Trial Comparing Spinal Laminectomy to Laminectomy With Instrumented Pedicle Screw Fusion for Lumbar Stenosis With Grade I Spondylolisthesis
In Brief
A Phase 3 clinical trial evaluating Lumbar Laminectomy with Instrumented Pedicle Screw Fusion and Lumbar Laminectomy for Spinal Stenosis and Spondylolisthesis. Completed, enrolled 66 participants across 5 sites.
Detailed Summary
The purpose of the study is to determine the proper use of lower back screws and rods (instrumentation) and bony fusion in subjects with one level of degenerative spinal narrowing (stenosis) compressing nerves to the legs with one spinal bone slipping forward on another (spondylolisthesis). There are two types of operations that surgeons perform for this problem. Some spinal surgeons remove some bone in the back (laminectomy) to decompress the nerves. Other surgeons perform a laminectomy (decompression) as above, but feel that it is also important to strengthen the back by placing screws and rods into the spine and adding more bone to obtain a new bridge of bone away from the nerves (decompression with instrumented fusion). This study aims to test the hypothesis that adding instrumented fusion to a decompression for this spinal problem will improve long term patient outcomes.
Study Details
Timeline
Interventions
Removal of bone to decompress spinal nerves with placement of spinal screws and extra bone to strengthen the spine
Removal of bone to decompress spinal nerves