At a glance
ClinicalIndex Comparison Record- ✓Age 15 years or older
- ✓Clinically-evident facial acne
- ✓Generally good health
- ✓Able to comply with protocol and attend all scheduled appointments in Ann Arbor, Michigan area
- ✕Oral retinoid (Accutane) use within 6 months
- ✕Systemic acne therapies (oral antibiotics) within 4 weeks
- ✕Topical acne therapies (retinoids, antibiotics) within 2 weeks
- ✕Prior microdermabrasion or superficial chemical peels at treatment sites within 2 months
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Photodynamic Therapy in the Treatment of Acne Vulgaris
In Brief
A Phase 2 clinical trial evaluating V-Beam laser, Candela Corp., 595 nm wavelength for Acne Vulgaris. Completed, enrolled 44 participants across 1 site.
Detailed Summary
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin. This type of laser treatment creates changes in a layer of the skin called the dermis without causing an open wound in the skin. The use of non-ablative laser therapy, together with application of a photo-sensitizer (substance that makes the skin more sensitive to light), may improve the appearance of acne. The idea behind the photo-sensitizer is that it is supposed to make the laser more effective than using just the laser alone. It is not yet clear how much improvement can be seen with these treatments or exactly how the skin's response causes these improvements. In this study, we are interested in learning how well such a laser works to improve the symptoms of acne, as well as how much the photo-sensitizer actually enhances the efficacy of the laser.
Study Details
Timeline
Interventions
Subjects will receive a series of up to 6 laser therapy sessions with a treatment interval of from approximately 1 to 4 weeks. In all cases, laser treatment parameters will be within the guidelines normally used clinically with the V-Beam laser, and thus fluences used will not exceed 15 J/cm2.