CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 221 enrolled
Drug / intervention
ACT (Adjustable Continence Therapy)device
Likely dose
ACT (Adjustable Continence Therapy) surgically implanted periurethral prosthetic deviceAI-extracted
Key inclusion· 6
  • Female, age 18 or older
  • Diagnosed with stress urinary incontinence with or without urethral hypermobility
  • Candidate for surgical intervention for stress incontinence
  • Failed at least 6 months of previous conservative or surgical treatments (e.g., pelvic floor exercises, electrical stimulation, prior surgical procedures)
Key exclusion· 13
  • Pregnant or lactating
  • Life expectancy less than one year
  • Insulin-dependent diabetic
  • Auto-immune disease

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00113555
NCT00113555N/ACompleted

Clinical Investigation of an Adjustable Continence Therapy (ACT) Periurethral Prosthetic System for Treatment of Female Stress Urinary Incontinence With or Without Hypermobility

Uromedica·interventional·Posted Jun 9, 2005·Updated Jul 9, 2018

In Brief

A clinical study evaluating ACT (Adjustable Continence Therapy) for Urinary Incontinence. Completed, enrolled 221 participants across 7 sites in 2 countries.

Detailed Summary

The purpose of this study is to evaluate the safety and effectiveness of a minimally invasive surgical procedure in up to 160 implanted female patients in which two adjustable balloons (one on each side of the urethra) are implanted to treat urinary stress incontinence. The results will be analyzed to demonstrate the effects of the device as well as its associated risks. Therapeutic success will be based on whether the patients demonstrate at least a one-grade (mean) reduction in the Stamey score at 12 months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

N/ACompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 9, 2005
Enrollment StartDec 1, 2001
Primary CompletionJul 1, 2008
Study CompletionNov 1, 2010
TodayJul 2, 2026
Enrollment to primary: 6.6 yearsPosted 21.1 years ago

Interventions

ACT (Adjustable Continence Therapy)device

surgically implanted device