CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,704 enrolled
Drug / intervention
temporary discontinuation of hormone therapy for 1 month +1 moreother
Likely dose
Temporary discontinuation of HRT for 1 or 2 months prior to screening mammogramAI-extracted
Key inclusion· 4
  • ✓One or more prior screening mammograms at Group Health Cooperative within the past 2 years
  • ✓Currently taking HRT
  • ✓Taking HRT at time of prior screening mammogram
  • ✓Due for a screening mammogram
Key exclusion· 7
  • ✕Entirely fatty breast density (BI-RADS 1)
  • ✕Previous cardiovascular events including heart surgery, catheterization, stent, bypass, angioplasty, stroke, or DVT
  • ✕Previous breast cancer
  • ✕History of breast implants

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00117663
NCT00117663N/ACompleted
CompareCT.gov

A Population-Based Randomized Trial to Assess the Effects of Short-Term Cessation of Hormone Replacement Therapy (HRT) on Mammography Assessments and Breast Density

Kaiser Permanente·interventional·Posted Jul 8, 2005·Updated Apr 4, 2024

In Brief

A clinical study evaluating temporary discontinuation of hormone therapy for 1 month and temporary discontinuation of hormone therapy for 2 months for Breast Cancer. Completed, enrolled 1,704 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether cessation of hormone replacement therapy for one or two months before a screening mammogram will improve its performance by decreasing breast density.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Cancer
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 8, 2005
Enrollment StartNov 1, 2004
Primary CompletionNov 1, 2007
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 21.0 years ago

Interventions

temporary discontinuation of hormone therapy for 1 monthother

temporary discontinuation of hormone replacement therapy for 1 month prior to screening mammogram.

temporary discontinuation of hormone therapy for 2 monthsother

temporary discontinuation of hormone replacement therapy for 2 months prior to screening mammogram