CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Total Surface Bearing Suction Socket +1 moredevice
Likely dose
Not stated in record
Key inclusion· 7
  • Age 18 to <70 years
  • Below-knee amputation, one side only
  • For traumatic amputation without diabetes/vascular disease: ≥6 months post-amputation and ≥4 months prosthesis use
  • For diabetes/vascular amputation: ≥1 year prosthesis use
Key exclusion· 4
  • Pain in legs or any condition that interferes with walking
  • Ulcer on residual limb
  • Active tumor or ongoing tumor treatment (if amputation was due to tumor or infection)
  • Fall within last 3 months

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00117793
NCT00117793N/ACompleted

Vacuum Suspension: Effects on Tissue Oxygenation, Activity and Fit

US Department of Veterans Affairs·interventional·Posted Jul 8, 2005·Updated Aug 15, 2014

In Brief

A clinical study evaluating Total Surface Bearing Suction Socket and Vacuum assisted socket system for Amputation and 3 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The fit of the residual limb within a prosthetic socket is a primary concern for many amputees. A poor fit can lead to skin irritation, tissue breakdown, and pain. Further, amputees with diabetes or vascular dysfunction often have difficulty maintaining healthy residual limb tissue; a condition that could be mitigated by the application of negative pressure (i.e., vacuum suspension). The aim of this research is to characterize the residual limb response to a vacuum suspension system and to measure prosthetic performance in comparison to a typical suction suspension system. The proposed research plan involves two sets of human subject experiments: (1) prospective, randomized cross-over study to quantify performance of a vacuum suspension system as compared to a total surface bearing suction socket in terms of pistoning, maintaining limb volume, step counts, and subjective measures of fit and (2) measurement of transcutaneous oxygen tension as a function of vacuum pressure.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 8, 2005
Enrollment StartAug 1, 2005
Primary CompletionSep 1, 2008
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 21.0 years ago

Interventions

Total Surface Bearing Suction Socketdevice

Current clinical practice

Vacuum assisted socket systemdevice

Novel socket system