At a glance
ClinicalIndex Comparison Record- ✓Age ≥50 years and residing in the community
- ✓Probable Alzheimer's disease diagnosed by DSM-IV and NINCDS-ADRDA criteria
- ✓CT or MRI brain scan and medical workup compatible with AD diagnostic criteria
- ✓MMSE score 3–14
- ✕Non-English speaking patient and/or caregiver
- ✕Dementia due to conditions other than Alzheimer's disease
- ✕Vascular dementia or modified Hachinski Ischemic Rating scale >4
- ✕Major depressive disorder
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: A Randomized Controlled Trial
In Brief
A Phase 4 clinical trial evaluating Individualized management of AD including caregiver training and Memantine for Alzheimer's Disease. Completed, enrolled 20 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether a comprehensive, individualized management approach with caregiver training and medication with memantine will alleviate symptoms in community dwelling patients with moderate to severe Alzheimer's disease.
Study Details
Timeline
Interventions
Individualized management program: consists of home visits to get the patient exercising, doing enjoyable activities and cognitive stimulation, educational sessions for caregivers on coping with difficult situations and a caregiver support group to help with questions and emotional concerns.
Patients receive 10 milligrams of memantine twice daily.