At a glance
ClinicalIndex Comparison Record- ✓Migraine with or without aura; probable migraine without aura
- ✕Secondary headache
- ✕Allergy, contraindication or intolerance to study medication
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Parenteral Corticosteroids as Adjuvant Therapy for Migraine Headaches
In Brief
A Phase 3 clinical trial evaluating Dexamethasone and Placebo for Migraine. Completed, enrolled 205 participants across 3 sites.
Detailed Summary
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines. Another problem with migraines is that although many times they get better after intravenous (IV) treatment in the emergency room (ER), about 1/3 of the time migraines recur the next day. The purpose of this research project is to see if adding a medication called dexamethasone to standard ER therapy will help patients get better quicker and stay pain-free more often than if they receive placebo.
Study Details
Timeline
Interventions
Dexamethasone 10mg IV
Placebo Dexamethasone 10mg IV