CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 36 enrolled
Drug / intervention
Carvedilol +1 moredrug
Likely dose
Carvedilol 25 mg twice daily or Metoprolol 200 mg twice dailyAI-extracted
Key inclusion· 7
  • ✓Age 30-80 years old
  • ✓Documented history of type 2 diabetes
  • ✓Stable ACE/ARB regimen for at least 30 days before and throughout study
  • ✓Stable anti-diabetic regimen throughout study
Key exclusion· 12
  • ✕Uncontrollable or symptomatic arrhythmias
  • ✕Unstable angina
  • ✕Sick sinus syndrome or second or third degree heart block
  • ✕Decompensated heart failure

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00123604
NCT00123604Phase 4Completed
CompareCT.gov

Effects of Carvedilol and Metoprolol on Endothelial Function in Hypertensive Patients With Type 2 Diabetes Mellitus

St. Paul Heart Clinic·interventional·Posted Jul 25, 2005·Updated Nov 18, 2014

In Brief

A Phase 4 clinical trial evaluating Carvedilol and Metoprolol for Hypertension and Type 2 Diabetes Mellitus. Completed, enrolled 36 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the vascular effects of two commonly used blood pressure medications, carvedilol and metoprolol in hypertensive patients with type 2 diabetes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension, Type 2 Diabetes Mellitus
CountriesUnited States
CollaboratorsGlaxoSmithKline

Timeline

Phase 4CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 25, 2005
Enrollment StartJun 1, 2004
Primary CompletionJun 1, 2006
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 20.9 years ago

Interventions

Carvediloldrug

25 mg twice daily for five months.

Metoprololdrug

200 mg twice daily for five months.