CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Control +1 moreother
Likely dose
Not stated in record
Key inclusion· 5
  • Clinical diagnosis of cerebrovascular accident (stroke), single event
  • Unilateral hemiplegia (one-sided paralysis)
  • Between 6 and 18 months post-stroke
  • Impairment of upper-extremity function with preserved motor capability (partial range of motion out of plane of gravity at shoulder, elbow, wrist; at least 10 degrees wrist motion and finger flexion/extension in 2 fingers)
Key exclusion· 4
  • Unstable or uncontrolled blood pressure
  • Uncontrolled seizures
  • Flaccid hemiplegia (complete loss of muscle tone in the paralyzed limb)
  • Severe cognitive impairment

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00125658
NCT00125658N/ACompleted

Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis

VA Office of Research and Development·interventional·Posted Aug 1, 2005·Updated Jun 23, 2017

In Brief

A clinical study evaluating Control and Experimental for Cerebrovascular Accident. Completed, enrolled 14 participants across 1 site.

Detailed Summary

The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the relationship between impairment and motor disability in post-stroke hemiparesis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 1, 2005
Enrollment StartFeb 1, 2008
Primary CompletionJun 1, 2009
Study CompletionSep 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 20.9 years ago

Interventions

Controlother

Following an initial testing session, you will complete a 5 week no training period. At the end of this period you will then participate in a 20 week therapy program - 10 weeks of Functional Task Practice (FTP) followed by 10 weeks of Power training (dynamic resistance exercise). Each 10 week block has 30 therapy sessions for a total of 60 sessions, each lasting approximately 1-1/2 hours. Follow up evaluations will be scheduled at 6 months and 12 months after completion of the entire 20 week therapy program.

Experimentalother

Following an initial testing session, you will complete a 5 week no training period. At the end of this period you will then participate in a 20 week therapy program - 10 weeks of Power training (dynamic resistance exercise) followed by 10 weeks of Functional Task Practice (FTP). Each 10 week block has 30 therapy sessions for a total of 60 sessions, each lasting approximately 1-1/2 hours. Follow up evaluations will be scheduled at 6 months and 12 months after completion of the entire 20 week therapy program.