At a glance
ClinicalIndex Comparison Record- ✓Age over 40 years
- ✓Scheduled for pneumonectomy or lobectomy
- ✕History of atrial fibrillation
- ✕Prior severe side effects from amiodarone
- ✕Elevated liver enzymes >3× upper limit of normal
- ✕QTc interval >450 ms
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Prevention of Atrial Fibrillation Following Noncardiac Thoracic Surgery
In Brief
A Phase 4 clinical trial evaluating Amiodarone for Atrial Fibrillation. Completed, enrolled 130 participants across 1 site.
Detailed Summary
The investigators hypothesize that the medication amiodarone decreases the incidence of atrial fibrillation (AF) following non-cardiac open-chest surgery. Their specific aims are to: * Determine the effectiveness of amiodarone for the prevention of AF following non-cardiac open-chest surgery; * Determine the influence of the prevention of AF following non-cardiac thoracic surgery on post-surgical duration of stay in the Intensive Care Unit (ICU); post-surgical duration of stay in a hospital unit that employs cardiac monitoring; and duration of post-surgical hospital stay; and * Determine the safety of amiodarone for the prevention of AF following non-cardiac open-chest surgery.