CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 142 enrolled
Drug / intervention
Nutropin AQ growth hormone +1 moredrug
Likely dose
Nutropin AQ growth hormone by injection every night for 6 months; specific dose not specified in published protocolAI-extracted
Key inclusion· 3
  • Visceral adiposity: waist circumference ≥88 cm for women or ≥102 cm for men AND BMI ≥25 kg/m2
  • IGF-I levels within the lowest 2 quartiles for age and gender
  • Willingness to maintain current activity level and diet throughout study
Key exclusion· 8
  • Diabetes mellitus (fasting plasma glucose >126 mg/dL or 2-hour post-OGTT plasma glucose >200 mg/dL)
  • Current smoking
  • Weight exceeding 280 pounds
  • History of cardiovascular disease

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00131378
NCT00131378N/ACompleted

Growth Hormone, Cardiovascular Risk, and Visceral Adiposity

Massachusetts General Hospital·interventional·Posted Aug 18, 2005·Updated Mar 11, 2016

In Brief

A clinical study evaluating Nutropin AQ growth hormone and Placebo Growth Hormone for Obesity. Completed, enrolled 142 participants across 1 site.

Detailed Summary

This study will compare growth hormone levels and cardiovascular risk markers in normal weight and overweight women and men. In women and men with increased abdominal weight, growth hormone (GH) versus placebo will be administered and effects on cardiovascular risk, insulin resistance and body composition will be measured.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 18, 2005
Enrollment StartNov 1, 2004
Primary CompletionNov 1, 2012
Study CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 8 yearsPosted 20.9 years ago

Interventions

Nutropin AQ growth hormonedrug

Participants will give themselves injections of growth hormone every night for 6 months.

Placebo Growth Hormonedrug

Participants will give themselves injections of placebo growth hormone every night for 6 months.