CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 17 enrolled
Drug / intervention
N-Acetylcysteine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00136825
NCT00136825Phase 1Completed
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N-acetylcysteine as Treatment in Cocaine Addiction

National Institute on Drug Abuse (NIDA)·interventional·Posted Aug 29, 2005·Updated Jan 12, 2017

In Brief

A Phase 1 clinical trial evaluating N-Acetylcysteine and Placebo for Cocaine-Related Disorders. Completed, enrolled 17 participants across 1 site.

Detailed Summary

Recent findings have suggested that N-acetylcysteine (NAC) substantially reduces cocaine drug-seeking behavior in formerly cocaine dependent rats. The purpose of this study is to determine the safety, tolerability, and cue reactivity effects of NAC in cocaine dependent individuals and non-dependent healthy controls.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine-Related Disorders
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 29, 2005
Enrollment StartMar 1, 2003
Study CompletionSep 1, 2005
TodayJul 2, 2026
Posted 20.8 years ago

Interventions

N-Acetylcysteinedrug

Placebodrug