CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 142 enrolled
Drug / intervention
Coronary artery bypass graft (CABG) surgeryprocedure
Likely dose
Not stated in record
Key inclusion· 4
  • ✓On waiting list for clinically-indicated myocardial revascularization surgery
  • ✓Aged 40-70 years
  • ✓Significant stenosis (≥70%) in the circumflex territory on preoperative angiograms
  • ✓Negative Allen's test (return of palmar circulation within 5 seconds of releasing ulnar artery compression)
Key exclusion· 3
  • ✕Poor left ventricular function (LV ejection fraction <25%)
  • ✕Severe diffuse peripheral vascular disease or bilateral varicose venous disease
  • ✕Inability to comply with angiographic follow-up at 3 months or/and 5 years

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00139399
NCT00139399Phase 3Completed
CompareCT.gov

A Randomised Controlled Trial to Compare Angiographic Patency of Radial Artery Versus Saphenous Vein Used as Free Aorto-coronary Grafts in Coronary Revascularization

Imperial College London·interventional·Posted Aug 31, 2005·Updated Jun 25, 2019

In Brief

A Phase 3 clinical trial evaluating Coronary artery bypass graft (CABG) surgery for Coronary Arteriosclerosis. Completed, enrolled 142 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether the radial artery (artery in the arm) or saphenous vein (vein in the leg), when used as bypass grafts for coronary artery bypass surgery, have a greater patency rate (degree of opening)at 5 years after surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Arteriosclerosis
CountriesUnited Kingdom
CollaboratorsThe Royal College of Surgeons of England, Royal Brompton & Harefield NHS Foundation Trust, National Heart Foundation, Australia, Victor Phillip Dahdaleh Charitable Foundation

Timeline

Phase 3CompletedFinished
199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 31, 2005
Enrollment StartMay 1, 1998
Primary CompletionJul 1, 2006
Study CompletionNov 1, 2006
TodayJul 2, 2026
Enrollment to primary: 8.2 yearsPosted 20.8 years ago

Interventions

Coronary artery bypass graft (CABG) surgeryprocedure

Patients were randomized to receive either a radial artery or a long saphenous vein graft to the left circumflex coronary artery territory during CABG surgery