At a glance

ClinicalIndex Comparison Record

Phase 3Completed· 5,107 enrolled

Drug / intervention

One shock per minute AED protocol +1 moreother

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00139542

NCT00139542Phase 3Completed

Compare CT.gov

Automated External Defibrillator (AED) Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"

Fire Brigade Of Paris Emergency Medicine Dept·interventional·Posted Aug 31, 2005·Updated May 11, 2009

In Brief

A Phase 3 clinical trial evaluating One shock per minute AED protocol and Guidelines 2000 AED protocol for Heart Arrest and Ventricular Fibrillation. Completed, enrolled 5,107 participants across 1 site.

Detailed Summary

The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressions. The researchers propose to decrease the periods of interruption of cardiopulmonary resuscitation (CPR), while keeping the principle of early defibrillation.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsHeart Arrest, Ventricular Fibrillation

CountriesFrance

CollaboratorsBrigade de Sapeurs Pompiers de Paris, Physio-Control, Inc, A division of Medtronic

Timeline

Phase 3CompletedFinished

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

First PostedAug 2005

Enrollment StartSep 2005

Primary CompletionMar 2007

Study CompletionJun 2008

TodayJul 2026

First PostedAug 31, 2005

Enrollment StartSep 1, 2005

Primary CompletionMar 1, 2007

Study CompletionJun 1, 2008

TodayJul 2, 2026

Enrollment to primary: 1.5 yearsPosted 20.8 years ago

Interventions

One shock per minute AED protocolother

Single shocks; No post-shock pulse checks; 60 sec CPR before first shock; 30 sec CPR between rhythm analysis and shock delivery.

Guidelines 2000 AED protocolother

Up to 3 consecutive shocks in a stack; No initial CPR prior to the first shock; Post-shock pulse checks after each non-shockable rhythm analysis; 60 sec CPR after each non-shockable rhythm analysis.