CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 47 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Key inclusion· 3
  • ✓Girls aged 12-18 years
  • ✓Obese subjects: BMI >95th percentile for age and sex
  • ✓Normal-weight controls: BMI 15th-85th percentile for age and sex
Key exclusion· 8
  • ✕History of conditions affecting GH, ghrelin, cortisol, or insulin secretion (eating disorder, diabetes, hypertension, thyroid disease, Cushing's syndrome, liver disease, renal failure, GH or cortisol excess/deficiency)
  • ✕Medications affecting glucose, lipids, or hormone secretion (rhGH, glucocorticoids, birth control pills)
  • ✕Pregnancy
  • ✕Smoking or substance abuse

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00140842
NCT00140842N/ACompleted
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Neuroendocrine Modulation of Metabolic Effects in Overweight Adolescents

Massachusetts General Hospital·observational·Posted Sep 1, 2005·Updated Nov 2, 2021

In Brief

An observational study for Obesity. Completed, enrolled 47 participants across 1 site.

Detailed Summary

This study will examine hormonal differences in ghrelin and growth hormone in obese and normal weight adolescents and their relationship to body composition and insulin resistance. The study will also investigate the effect of the macronutrient composition of a meal on postprandial ghrelin levels and whether ghrelin responses will predict the degree of hunger and caloric intake at a subsequent meal.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 1, 2005
Enrollment StartMay 1, 2005
Primary CompletionJun 1, 2007
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 20.8 years ago