CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 577 enrolled
Drug / intervention
olmesartan medoxomil +1 moredrug
Likely dose
Olmesartan medoxomil 10-40 mg orally once dailyAI-extracted
Key inclusion· 4
  • Clinical diagnosis of diabetic nephropathy in patients with type 2 diabetes
  • Albumin-to-creatinine ratio ≥300 mg/g creatinine in first morning urinalysis (overt proteinuria)
  • Serum creatinine 1.0-2.5 mg/dL in women
  • Serum creatinine 1.2-2.5 mg/dL in men
Key exclusion· 12
  • Type 1 diabetes
  • Non-diabetic nephropathy
  • Myocardial infarction or coronary artery bypass grafting within 3 months
  • Percutaneous coronary intervention (PCI) within 6 months

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00141453
NCT00141453Phase 3Completed

CS-866DM Phase 3 Clinical Study: A Double-Blind Controlled Trial in Patients With Diabetic Nephropathy and Overt Proteinuria Secondary to Type 2 Diabetes Mellitus

Daiichi Sankyo Co., Ltd.·interventional·Posted Sep 1, 2005·Updated May 10, 2011

In Brief

A Phase 3 clinical trial evaluating olmesartan medoxomil and Placebo Tablets for Diabetic Nephropathy and 2 related conditions. Completed, enrolled 577 participants across 2 sites in 2 countries.

Detailed Summary

The purpose of the study is to evaluate the effectiveness and safety of olmesartan versus placebo on the progression of diabetic renal disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina, Japan
Collaborators--

Timeline

Phase 3CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 1, 2005
Enrollment StartApr 1, 2003
Primary CompletionAug 1, 2008
Study CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 20.8 years ago

Interventions

olmesartan medoxomildrug

Tablets 10, 20, or 40 mg

Placebo Tabletsdrug

Matching placebo tablets